Even partial loss of the gene impairs the mouse brain’s ability to respond to sensory experiences, which may explain why people with SYNGAP1 mutations tend to have learning difficulties and a high pain tolerance.

The post Autism-linked gene SYNGAP1 molds synaptic plasticity, learning appeared first on Spectrum | Autism Research News.

Preliminary results suggested the treatment is no better than placebo at reducing the severity of core autism traits.

The post French pharma firms terminate trials of bumetanide for autism appeared first on Spectrum | Autism Research News.

Altered electrical activity in the neurons of mice with a mutated copy of SCN2A may explain the animals’ autism-like social behaviors.

The post Model mice hint at sodium channel gene’s contribution to autism appeared first on Spectrum | Autism Research News.

Deleterious mutations in an autism-associated gene can make neurons hyperexcitable, raising the risk of epileptic seizures.

The post How mutations in top autism gene could lead to seizures appeared first on Spectrum | Autism Research News.

A transplant of inhibitory neurons during the second week of life prevents social difficulties and a brain signaling imbalance in mice missing a copy of FOXG1.

The post Critical time window flagged for autism gene’s influence appeared first on Spectrum | Autism Research News.