Common and rare variants in or near autism-associated genes can have opposite effects on cognition.

The post Autism-linked genetic variants increase, decrease intelligence appeared first on Spectrum | Autism Research News.

Spontaneous genetic mutations contribute to autism in 30 to 39 percent of all people with the condition, and 52 to 67 percent of autistic children whose siblings do not also have the condition.

The post Analysis ups estimate of spontaneous mutations’ role in autism appeared first on Spectrum | Autism Research News.

Spontaneous mutations in parts of the genome that regulate gene EBF3 appear to contribute to autism risk.

The post Mutations in the noncoding genome contribute to autism appeared first on Spectrum | Autism Research News.

Mosaic mutations, which affect only some of the body’s cells, play a small but meaningful role in autism. Though they are difficult to study, researchers are working to master their complexity.

The post Patchwork mutations present a new frontier for autism research appeared first on Spectrum | Autism Research News.

Cross-species comparisons can help make sense of subtle genetic variants in people with autism and identify hundreds of new genes that may contribute to the condition.

The post Evolutionary approach reveals impact of missense variants in autism appeared first on Spectrum | Autism Research News.